mounjaro vs ozempic

mounjaro vs ozempic

mounjaro vs ozempic

Overview of mounjaro and ozempic.

Ozempic and Mounjaro are FDA-approved to treat Type 2 diabetes and belong to the GLP-1 class of drugs. In studies, Mounjaro was more effective than Ozempic for blood sugar control and weight loss. Mounjaro is slightly more expensive than Ozempic and may have additional side effects[1].

Both Mounjaro and Ozempic are prescription medicines, used alongside diet and exercise, to help control blood sugar (glucose) levels in adults with type 2 diabetes. Ozempic is also approved to lower the risk of a major cardiovascular event (like a heart attack or stroke) in patients with type 2 diabetes. Mounjaro has not yet received this indication, although studies are ongoing[2].

This is not all the information you need to know about Mounjaro or Ozempic for safe and effective use and does not take the place of your doctor’s directions. Review the full patient medication guide and discuss this information and any questions you have with your doctor or other health care provider[2].

Key differences between mounjaro and ozempic.

Mounjaro and Ozempic are both in the class of drugs known as incretin mimetics but have some differences. Mounjaro acts on both GIP and GLP-1 receptors, while Ozempic acts only on GLP-1 receptors; however, both drugs are effective treatments for type 2 diabetes[2].

Mounjaro and Ozempic work in relatively similar ways, but since the active ingredient is different, individuals may find that one medication gives them more side effects compared to the other — or they do not see the weight loss results from their current medication[3].

Mounjaro® and Ozempic® have distinct active ingredients: tirzepatide and semaglutide, respectively. However, both of these drugs are GLP-1 agonists, which bind to GLP-1 receptors, simulate a feeling of satiety, and signal the pancreas to produce insulin[4].

Factors to consider when choosing between mounjaro and ozempic.

Whether you should take Ozempic or Mounjaro depends on your individual treatment needs. Mounjaro is more effective for weight loss and lowering A1C, but it could also come with a greater risk of side effects — particularly severe gastrointestinal side effects[1].

Mounjaro and Ozempic can also vary in cost and availability, depending on the state that you’re living in, your healthcare insurance, and other factors. For example, Ozempic has long been in high demand (resulting in low availability within the US) for both type 2 diabetics and those wanting to try it out for weight loss, so choosing to switch to Mounjaro may be an easier and more convenient option[3].

Cost – Both Ozempic and Mounjaro are relatively similar price-wise, but in some cases, Mounjaro is seen to be slightly more expensive. This can also depend on whether you have health insurance and whether you buy it from an online retailer versus a pharmacy[3].


  1. Ozempic vs. Mounjaro. (n.d.) Retrieved October 5, 2023, from
  2. Mounjaro vs Ozempic: How do they compare?. (n.d.) Retrieved October 5, 2023, from
  3. Mounjaro vs. Ozempic: How These Medications Compare. (n.d.) Retrieved October 5, 2023, from
  4. Understanding Ozempic® vs. Mounjaro® for Weight Loss. (n.d.) Retrieved October 5, 2023, from

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